Rad9A (D2J4P) Rabbit mAb
货号：
14484S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 14484S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | DNA damage resulting from genotoxic stress activates cellular checkpoints that prevent or delay cell division until either damaged DNA is repaired or the cell follows an apoptotic pathway. The Rad9 homolog A (Rad9A, Rad9) protein is part of a checkpoint protein complex that acts as an early sensor of DNA damage. Together with the Hus1 and Rad1 checkpoint proteins, Rad9 forms a heterotrimeric 9-1-1 complex with a ring structure similar to the processivity factor PCNA. The 9-1-1 complex induces multiple signaling pathways, including the ATM and ATR-activated DNA repair pathways (1,2). A functional 9-1-1 complex is required for ATR-dependent S phase checkpoint signaling (3). |
| 存放说明 | -20C |
| 计算分子量 | 60 |
参考图片Western blot analysis of extracts from various cell lines using Rad9A (D2J4P) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower). |
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing Myc/DDK-tagged full-length human Rad9A (Rad9A-Myc/DDK; +) protein, using Rad9A (D2J4P) Rabbit mAb (upper) or Myc-Tag (71D10) Rabbit mAb #2278 (lower). |
