货号 | 4357S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | RagA (D8B5) Rabbit mAb detects endogenous levels of total RagA protein. It may also detect endogenous levels of total RagB protein. |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | mTORC1 kinase complex is a critical component in regulating cell growth (1,2). Its activity is modulated by energy levels, growth factors and amino acids (3,4). Recent studies found that RagA, RagB, RagC and RagD, the four related GTPases, interact with raptor in mTORC1 (1,2). These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals (1,2). |
存放说明 | -20C |
计算分子量 | 30 |
Western blot analysis of extracts from mIMCD3, KNRK and COS7 cells using RagA (D8B5) Rabbit mAb. Western blot 分析mIMCD3, KNRK和COS7细胞的提取物,所用抗体为RagA (D8B5) Rabbit mAb兔单抗。 | |
Western blot analysis of extracts from 293 and PANC-1 cells using RagA (D8B5) Rabbit mAb. Western blot 分析293 和PANC-1 细胞的提取物,所用抗体为RagA (D8B5) Rabbit mAb兔单抗。 |