| 货号 | 8150S |
| 反应种属 | Human/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | RagB (D18F3) Rabbit mAb recognizes endogenous levels of total RagB protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | The mTORC1 kinase complex is a critical regulator of cell growth (1,2). Its activity is modulated by energy levels, growth factors, and amino acids via signaling through Akt, MAPK, and AMPK pathways (3,4). Recent studies found that the four related GTPases, RagA, RagB, RagC, and RagD, interact with raptor within the mTORC1 complex (1,2). These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals (1,2). |
| 存放说明 | -20C |
| 计算分子量 | 40 |
Western blot analysis of extracts from various cell lines using RagB (D18F3) Rabbit mAb. Western blot分析不同细胞系裂解物，所用抗体为RagB (D18F3) Rabbit mAb兔单抗。 |
