RanBP9 (D8M8D) Rabbit mAb
货号：
14638S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 14638S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit IgG |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | RanBP9 (RanBPM) is a Ran binding protein ubiquitously expressed and highly conserved in different organisms. It is a scaffolding protein that was identified as an interacting protein of MET inducing Ras- Erk activation (1). Several domains and motifs regulate the nuclear and cytoplasmic localization of RanBP9 (2). Research studies indicate that RanBP9 might contribute to the pathogenesis of Alzheimer’s Disease (AD). In addition to elevated expression levels in AD samples, this may involve interaction of RanBP9 with APP and BACE1 promoting endocytosis of APP and increased BACE1 mediated cleavage of APP to generate β-amyloid peptides (3). |
| 存放说明 | -20C |
| 计算分子量 | 80, 91 |
参考图片Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence® Control siRNA (Unconjugated) #6568 (-) or RanBP9 siRNA (+), using RanBP9 (D8M8D) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower). |
Western blot analysis of extracts from HeLa, NIH/3T3, and C2C12 cells using RanBP9 (D8M8D) Rabbit mAb. |
