货号 | 14794S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | W/IP |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | The X-linked RNA binding motif protein (RBMX, hnRNP G) is a multi-functional protein that is part of a heterogeneous nuclear ribonucleoprotein complex (1,2). This widely expressed protein is involved in the control of pre-mRNA splicing as part of the spliceosome. RBMX is important for the alternative splicing of many pre-mRNAs, including those that encode for dystrophin, tropomyosin, and survival motor neuron protein (SMN) in skeletal muscle and cardiac muscle (3,4). The RBMX protein is essential for the maintenance of proper sister chromatid cohesion prior to sister chromosome segregation during mitosis (5). Research studies show that RBMX accumulates at sites of DNA damage and that the presence of RBMX is required for homologous recombination repair (6). |
存放说明 | -20C |
计算分子量 | 42 |
Western blot analysis of extracts from various cell lines using RBMX/hnRNP G (D7C2V) Rabbit mAb. | |
Immunoprecipitation of RBMX/hnRNP G from HeLa cell extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or RBMX/hnRNP G (D7C2V) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using RBMX/hnRNP G (D7C2V) Rabbit mAb. |