REPS1 (D6F4) Rabbit mAb
货号：
6404S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 6404S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | REPS1 (D6F4) Rabbit mAb recognizes endogenous levels of total REPS1 protein. |
| 使用方法 | WB(1:1000)
IP (1:200) |
性能| 供应商 | CST |
| 背景 | REPS1 is a RalBP1-associated EH-homology domain containing protein. The sequence of REPS1 has an EH domain, followed by two proline-rich segments, and a C-terminal coiled-coil domain for binding to RalBP1 (1). The EH domain of REPS1 interacts with the NPF motif of Rab11-FIP2, mediates their colocalization to endosome vesicles, and influences EGFR endocytosis (2). The two proline-rich regions of REPS1 are important for binding to the SH3 domain of GRK/GRB2 and further regulate EGFR downstream signaling. The proline-rich regions of REPS1 have also been shown to interact with the SH3 domain of intersectin1 (ITSN1) and contribute to ITSN1/SGIP1/REPS1 complex formation on clathrin-coated pits. Three alternatively spliced isoforms of REPS1 have been identified. |
| 存放说明 | -20C |
| 计算分子量 | 125 |
参考图片Western blot analysis of extracts from various cell lines using REPS1 (D6F4) Rabbit mAb.对多个细胞系抽提物使用REPS1 (D6F4) Rabbit mAb兔单抗进行Western blot分析。 |
