货号 | 27182S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit IgG |
应用 | IHC-P/IF-F |
使用方法 | IHC-P(1:1000) IF-F (1:400) |
供应商 | CST |
背景 | Rhodopsin is the photoreceptor in the retinal rods. It is activated by photons, transduces visual information through its cognate G protein, transducin, and is inactivated by arrestin binding (1). Using atomic-force microscopy, rhodopsin was found to be arranged into paracrystalline arrays of dimers in mouse disc membranes (2). Rhodopsin is considered to be the prototype of G protein-coupled receptors (GPCRs), and is the first GPCR for which a crystal structure was solved (3). Research studies have linked mutations in the gene encoding rhodopsin to retinitis pigmentosa (4,5), a disease characterized by retinal degeneration resulting in reduced peripheral vision and night blindness (6). |
存放说明 | -20C |
计算分子量 | 37 |
Confocal immunofluorescent analysis of rat retina using Rhodopsin (D4B9B) Rabbit mAb (green) and GFAP (GA5) Mouse mAb #3670 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). | |
Immunohistochemical analysis of paraffin-embedded mouse retina using Rhodopsin (D4B9B) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded rat retina using Rhodopsin (D4B9B) Rabbit mAb. |