| 货号 | 8408S |
| 反应种属 | Human/Mouse/Rat/Monkey/Bovine/Pig |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed serine/threonine kinases characterized by two nonidentical, functional kinase domains (1) and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs) (2). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation (3). RSK1-3 are activated via coordinated phosphorylation by MAPKs, by autophosphorylation, and by phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters (3). |
| 存放说明 | -20C |
| 计算分子量 | 90 |
Western blot analysis of extracts from various cell lines using RSK1 (D6D5) Rabbit mAb.Western blot 检测细胞提取物：各种细胞系，使用的抗体是RSK1 (D6D5) Rabbit mAb。 | |
Western blot analysis of recombinant GST-tagged RSK1, RSK2, and RSK3 (2 μg each) using RSK1 (D6D5) Antibody #8408 (left panel), RSK2 (D21B2) Rabbit mAb #5528 (center panel) or GST Rabbit mAb #2625 (right panel).Western blot分析重组GST标记的RSK1, RSK2,RSK3 (每个样品2μg )，使用的抗体是RSK1 (D6D5) Antibody #8408 (左侧), RSK2 (D21B2) Rabbit mAb #5528 (中间)和GST Rabbit mAb #2625 (右侧)。 |
