SAT1 (D1T7M) Rabbit mAb
货号：
61586S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 61586S |
| 反应种属 | Human |
| 来源宿主 | Rabbit IgG |
| 应用 | W/IP |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Spermidine/spermine N1-acetyltransferase 1 (SAT1) is a key enzyme in polyamine metabolism. It acts by acetylating spermidine and spermine using acetyl-coenzyme A (CoA), which alters their charge and facilitates their secretion (1,2). SAT1 activity is tightly controlled in cells, but increases quickly by excess polyamines. Its activity can also be induced by a number of other stimuli, such as oxidative stress, heat shock, insulin-like growth factor-I, and cytotoxins (2-4). Research studies have found that SAT1 is overexpressed in glioblastoma multiforme (GBM), which suggest that SAT1 may be a potential therapeutic target for GBM (5). |
| 存放说明 | -20C |
| 计算分子量 | 18 |
参考图片Western blot analysis of extracts from SK-MEL-28 cells untreated (-) or treated with N1, N11-diethylnorspermine (DENSPM) (10 μM, 24 hr; +), using SAT1 (D1T7M) Rabbit mAb. |
