SGK2 (D7G1) Rabbit mAb
货号：
7499S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 7499S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | SGK2 (D7G1) Rabbit mAb recognizes endogenous levels of total SGK2 protein. The antibody does not cross react with other SGK family members (e.g. SGK1 and SGK3). |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt (1). SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways (2,3). Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation (4-6). SGK also plays an important role in activating certain potassium, sodium, and chloride channels, suggesting its involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion (2). SGK is negatively regulated by ubiquitination and proteasome degradation (7). |
| 存放说明 | -20C |
| 计算分子量 | 42 |
参考图片Western blot analysis of extracts from HT-29 cells, mouse liver, and rat liver using SGK2 (D7G1) Rabbit mAb. Western blot分析HT-29细胞，小鼠肝脏和大鼠肝脏裂解物，所用抗体为SGK2 (D7G1) Rabbit mAb兔单抗。 |
