SMARCB1/BAF47 (D9C2) Rabbit mAb
货号：
8745S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 8745S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | SNF5 (D9C2) Rabbit mAb recognizes endogenous levels of total SNF5 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | ATP-dependent chromatin remodeling complexes play an essential role in the regulation of nuclear processes such as transcription and DNA replication and repair (1,2). The SWI/SNF chromatin remodeling complex consists of more than 10 subunits and contains a single molecule of either BRM or BRG1 as the ATPase catalytic subunit. The activity of the ATPase subunit disrupts histone-DNA contacts and changes the accessibility of crucial regulatory elements to the chromatin. The additional core and accessory subunits play a scaffolding role to maintain stability and provide surfaces for interaction with various transcription factors and chromatin (2-5). The interactions between SWI/SNF subunits and transcription factors such as nuclear receptors, p53, Rb, BRCA1, and MyoD facilitate recruitment of the complex to target genes to regulate gene activation, cell growth, cell cycle, and differentiation processes (1,6-9). |
| 存放说明 | -20C |
| 计算分子量 | 44 |
参考图片Western blot analysis of extracts from various cell lines using SNF5 (D9C2) Rabbit mAb. 使用SNF5 (D9C2) Rabbit mAb兔单抗，免疫印迹(Western blot)分析不同细胞中SNF5 (D9C2)蛋白水平。 |
