Sox2 (L73B4) Mouse mAb
货号：
4195S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4195S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | Sox2 (L73B4) Mouse mAb detects endogenous levels of total Sox2 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Embryonic stem cells are derived from the inner cell mass of the blastocyst and are unique in their pluripotent capacity and potential for self-renewal. Sox2 is one of a set of transcription factors that are crucial for the maintenance of pluripotency (1). Sox2, Oct-4, and Nanog cooperate in this network (1-3) and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency (4,5). Chromatin immunoprecipitation experiments have shown that Sox2 and Oct-4 bind to thousands of gene regulatory sites, highlighting the importance of these transcription factors in early embryonic development (6,7). It has recently been shown that Sox2 is amplified in lung and esophageal squamous cell tumors (8). |
| 存放说明 | -20C |
| 计算分子量 | 35 |
参考图片Western blot analysis of extracts of NTERA2 and NCCIT cells using Sox2 (L73B4) Mouse mAb.使用Sox2 (L73B4) Mouse mAb对NTERA2和NCCIT细胞提取物进行western blot分析。 |
