| 货号 | 8725S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IHC-P |
| 目标/特异性 | SPARC (D10F10) Rabbit mAb recognizes endogenous levels of total SPARC protein. |
| 使用方法 | WB(1:1000) IHC-P (1:2400) |
| 供应商 | CST |
| 背景 | SPARC (secreted protein acidic and rich in cysteine), also known as osteonectin and BM40, is a secreted matricellular glycoprotein that belongs to a group of functionally related glycoproteins that includes tenascins C and X, thrombospondins 1 and 2, and osteopontin (1). Members in this class of glycoproteins are involved in tissue renewal, tissue remodeling, and embryonic development and work by exerting counter-adhesive and antiproliferative effects that lead to changes in cell shape, disruption of cell adhesion, and inhibition of the cell cycle (2). SPARC is expressed at high levels in bone tissue but is widely distributed in many other tissues and cell types (3), and is known to be associated with tissues undergoing morphogenesis, angiogenesis, mineralization, and other pathological responses to injury and tumorigenesis (4,5). SPARC has also been linked with obesity and diabetes (6). |
| 存放说明 | -20C |
| 计算分子量 | 42 |
Western blot analysis of culture medium, from SPARC-secreting PYS-2 cells, using SPARC (D10F10) Rabbit mAb.使用SPARC (D10F10)兔单抗对SPARC-secreting的 PYS-2 细胞培养基进行western blot分析。 | |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using SPARC (D10F10) Rabbit mAb.使用SPARC (D10F10) 兔单抗对石蜡包埋的人肺癌组织进行免疫组化分析。 | |
Immunohistochemical analysis of paraffin-embedded human colon carcinoma using SPARC (D10F10) Rabbit mAb.使用SPARC (D10F10) 兔单抗对石蜡包埋的人结肠癌组织进行免疫组化分析。 |
