货号 | 14954S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit IgG |
应用 | W/IP |
使用方法 | WB(1:1000) IP (1:100) |
供应商 | CST |
背景 | Studies have shown that several cancers have reduced levels of Spry2 expression implicating Spry2 as a tumor suppressor (5-8). The regulation of Spry2 expression and activity appears to be a complex process involving casein kinase 1, Shp2 phosphatase, and Spry2-interacting partners (9-11). Phosphorylation of Tyr55 residue of Spry2 is required for the inhibitory function of Spry2 in FGF/MAPK signaling (12,13). |
存放说明 | -20C |
计算分子量 | 35 |
Western blot analysis of extracts from various cell lines using Spry2 (D3G1A) Rabbit mAb. | |
Immunoprecipitation of Spry2 protein from SK-MEL-5 cell extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, and lane 3 is Spry2 (D3G1A) Rabbit mAb. Western blot analysis was performed using Spry2 (D3G1A) Rabbit mAb. |