Kindlin-3 (D8I7V) Rabbit mAb【科瑞奥博】

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Kindlin-3 (D8I7V) Rabbit mAb

货号： 10459S 基本售价： 3360.0 元规格： -

产品信息

概述
货号	10459S
同种亚型	Rabbit IgG
反应种属	Human\Mouse\Rat
来源宿主	Rabbit IgG
应用	WB, IP , IHC-P , F
目标/特异性	Kindlin-3 (D8I7V) Rabbit mAb recognizes endogenous levels of total Kindlin-3 protein.
使用方法	W IP IHC-P F

性能
供应商	CST
灵敏度	Endogenous
背景	The kindlin family of focal adhesion proteins is involved in multiple biological processes, including integrin signaling, adhesion, migration, angiogenesis, differentiation, and mitotic spindle formation (1,2). Kindlin family members 1, 2, and 3 (FERM1, FERM2, and URP2) are differentially expressed in tissues. Kindlin-1 is primarily expressed in epithelial cells, kindlin-2 is ubiquitously expressed, and kindlin-3 expression is restricted to the hematopoietic system (3).
存放说明	-20C
计算分子量	75
参考文献	1 . Ye, F. and Petrich, B.G. (2011) Curr Opin Hematol 18, 356-60. 2 . Meves, A. et al. (2009) Trends Cell Biol 19, 504-13. 3 . Karaköse, E. et al. (2010) J Cell Sci 123, 2353-6. 4 . Fagerholm, S.C. et al. (2014) Am J Clin Exp Immunol 3, 37-42. 5 . Pasini, E.M. et al. (2006) Blood 108, 791-801. 6 . Tadokoro, S. et al. (2003) Science 302, 103-6. 7 . Wegener, K.L. et al. (2007) Cell 128, 171-82. 8 . Moser, M. et al. (2009) Science 324, 895-9. 9 . Malinin, N.L. et al. (2009) Nat Med 15, 313-8. 10 . Svensson, L. et al. (2009) Nat Med 15, 306-12.

参考图片

Flow cytometric analysis of HEL9217 cells using Kindlin-3 (D8I7V) Rabbit mAb (blue) compared to concentration-matched Rabbit (DA1E) mAb IgG XP^® Isotype Control #3900 (red). Anti-rabbit IgG (H+L), F(ab)₂ Fragment (Alexa Fluor^® 488 Conjugate) #4412 was used as a secondary antibody.

Western blot analysis of extracts from various cell lines using Kindlin-3 (D8I7V) Rabbit mAb.

Immunohistochemical analysis of paraffin-embedded human colon carcinoma using Kindlin-3 (D8I7V) Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right).

Immunohistochemical analysis of paraffin-embedded human non-Hodgkins lymphoma using Kindlin-3 (D8I7V) Rabbit mAb.

Immunohistochemical analysis of paraffin-embedded human tonsil using Kindlin-3 (D8I7V) Rabbit mAb.

Immunoprecipitation of Kindlin-3 protein from HEL9217 cell extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP^® Isotype Control #3900, and lane 3 is Kindlin-3 (D8I7V) Rabbit mAb. Western blot analysis was performed using Kindlin-3 (D8I7V) Rabbit mAb.