Synaptophysin (7H12) Mouse mAb (IF Formulated)
货号:
9020S 基本售价:
3360.0 元 规格:
100ul
产品信息
概述货号 | 9020S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Mouse |
应用 | IF-F |
目标/特异性 | Synaptophysin (7H12) Mouse mAb (IF Formulated) recognizes endogenous levels of total synaptophysin protein. |
使用方法 | IF-F(1:200) |
性能供应商 | CST |
背景 | Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4). |
存放说明 | -20C |
参考图片Confocal immunofluorescent analysis of mouse brain (left) and mouse retina (right) using Synaptophysin (7H12) Mouse mAb (IF Formulated) (green) and CNPase (D83E10) XP® Rabbit mAb (Alexa Fluor® 555 Conjugate) #5715 (red, left). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). 共聚焦免疫荧光分析小鼠大脑(左图)和小鼠视网膜(右图),使用的抗体是Synaptophysin (7H12) Mouse mAb (IF Formulated)(绿色)和CNPase (D83E10) XP® Rabbit mAb (Alexa Fluor® 555 Conjugate) #5715(红色,左)。蓝色伪彩=DRAQ5®#4084(荧光DNA染料)。 |