Synaptophysin (7H12) Mouse mAb
货号：
12270S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 12270S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | Synaptophysin (7H12) Mouse mAb recognizes endogenous levels of total synaptophysin protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4). |
| 存放说明 | -20C |
| 计算分子量 | 38 |
参考图片Western blot analysis of extracts from various tissues and cell lines using Synaptophysin (7H12) Mouse mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). Western blot 检测多种组织及细胞系提取物，使用的抗体是Synaptophysin (7H12) Mouse mAb 鼠单抗（上图）或β-Actin (D6A8) Rabbit mAb 兔单抗#8457（下图）。 |
