TAF1 (D6J8B) Rabbit mAb
货号：
12781S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 12781S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | TAF1 (D6J8B) Rabbit mAb recognizes endogenous levels of total TAF1 protein. This antibody also cross-reacts with protein of unknown origin at 45 kDa. |
| 使用方法 | WB(1:1000)
IP (1:100) |
性能| 供应商 | CST |
| 背景 | TATA-binding protein (TBP) is a ubiquitously expressed nuclear protein that functions at the core of the general transcription factor protein complex TFIID (1-3). TFIID, which contains TBP and 13 TBP-associated factors (TAFs), contributes to the formation of the transcription pre-initiation complex, an assembly of multiple protein complexes (TFIIA, TFIIB, TFIIE, TFIIF, TFIIH, and RNA polymerase II) that bind to a gene promoter during the initiation of transcription (1-3). Once the pre-initiation complex is formed, RNA polymerase II becomes competent for elongation and transcribes the body of a gene. TBP functions in the recruitment of TFIID by binding to the TATA-box sequence found approximately 25 base pairs upstream of the transcription start site of many protein-coding genes. In addition, many transcriptional activator proteins interact with TBP and various TAF proteins to facilitate recruitment of TFIID and formation of the pre-initiation complex. |
| 存放说明 | -20C |
| 计算分子量 | 250 |
参考图片Western blot analysis of extracts from Hep G2, SW620 and U-2 OS cells using TAF1 (D6J8B) Rabbit mAb.Western blot方法检测Hep G2, SW620和 U-2 OS细胞的提取物，使用的抗体为TAF1 (D6J8B) Rabbit mAb。 |
