货号 | 4169S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Mouse |
应用 | W/IP |
目标/特异性 | TFIIB (2F6A3H4) Mouse mAb detects endogenous levels of total TFIIB protein. |
使用方法 | WB(1:1000) IP (1:100) |
供应商 | CST |
背景 | TFIIB (also known as GTF2B, TF2B and general transcription factor IIB) is a ubiquitously expressed transcription factor that plays a central role in the assembly of the transcription pre-initiation complex through direct recruitment of RNA polymerase II (1,2). TFIIB functions as a bridge between promoter-bound TFIID and RNA polymerase II. In addition to interacting with promoter-bound TFIID and TFIIA, TFIIB makes extensive contacts with the core promoter via two independent DNA-binding modules. TFIIB may also be a target of transcriptional activator proteins that act to stimulate pre-initiation complex assembly. |
存放说明 | -20C |
计算分子量 | 32 |
Western blot analysis of extracts from various cell lines using TFIIB (2F6A3H4) Mouse mAb. 使用TFIIB (2F6A3H4) Mouse mAb鼠单抗,免疫印迹(Western blot)分析不同细胞系中TFIIB的蛋白水平。 |