| 货号 | 13077S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | Toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP, MAL) is a cytoplasmic protein containing an amino-terminal PIP2 binding site and a carboxy-terminal TIR domain. This adaptor protein mediates downstream signaling from associated toll-like receptors and is essential for MyD88-dependent TLR2 and TLR4 signaling (9,15-18). TIRAP is recruited to the plasma membrane by its PIP2 binding domain, where it mediates recruitment of MyD88 to initiate TLR signaling (15). |
| 存放说明 | -20C |
| 计算分子量 | 35 |
Western blot analysis of extracts from Raw 264.7, MEF, and A20 cells using TIRAP (D6M9Z) Rabbit mAb (Mouse Specific). | |
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing Myc/DDK-tagged full-length mouse TIRAP (mTIRAP-Myc/DDK; +), using TIRAP (D6M9Z) Rabbit mAb (Mouse Specific). |
