TorsinA (D-M2A8) Mouse mAb
货号：
2150S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2150S |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | TorsinA (D-M2A8) Mouse mAb detects endogenous levels of total torsinA protein. TorsinA (D-M2A8) Mouse mAb does not detect TorsinB (Hewett, J. et al., 2004). |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The neurological condition Dystonia is associated with sustained muscle contractions and abnormal posturing (1). TorsinA, torsinB, torp2A and torp3A belong to the family of ATPases associated with cellular activites (AAA+) and mutations in torsinA cause early onset dystonia (2). TorsinA has been shown to suppress intracellular protein aggregation in C. elegans and possesses chaperon activity. Interestingly, torsinA is highly expressed in dopaminergic neurons and associates with alpha-synuclein in Lewy bodies, which pathologically characterize Parkinsons Disease (3-5). |
| 存放说明 | -20C |
| 计算分子量 | 35 |
参考图片Western blot analysis of extracts from SH-SY5Y and U87MG cells, using TorsinA (D-M2A8) Mouse mAb. Western blot分析SH-SY5Y和U87MG细胞提取物，使用的抗体是TorsinA (D-M2A8) Mouse mAb 鼠单抗。 |
