| 货号 | 4710S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rat IgG2a |
| 应用 | W/IP/IHC-P/IF-IC |
| 目标/特异性 | TRAF1 (1F3) Rat mAb detects endogenous levels of total TRAF1 protein. |
| 使用方法 | WB(1:1000) IP (1:100) IHC-P (1:25) IF-IC (1:100) |
| 供应商 | CST |
| 背景 | TRAFs (TNF receptor-associated factors) are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular responses (1-3). Members of the TRAF family share a common carboxy-terminal "TRAF domain" which mediates interactions with associated proteins; many also contain amino-terminal Zinc/RING finger motifs. The first TRAFs identified, TRAF1 and TRAF2, were found by virtue of their interactions with the cytoplasmic domain of TNF-receptor 2 (TNFRII) (4). The six known TRAFs (TRAF1-6) act as adaptor proteins for a wide range of cell surface receptors and participate in the regulation of cell survival, proliferation, differentiation, and stress responses. |
| 存放说明 | -20C |
| 计算分子量 | 50 |
Western blot analysis of extracts from Raji and SR cells, using TRAF1 (1F3) Rat mAb. Western blot 检测 Raji 和 SR 细胞提取物，使用抗体为TRAF1 (1F3) Rat mAb 兔单抗。 | |
Immunofluorescent staining of Raji cells showing cytoplasmic staining, using TRAF1 (1F3) Rat mAb. 免疫荧光检测 Raji 细胞，细胞质染色成像，使用抗体为TRAF1 (1F3) Rat mAb 兔单抗。 | |
Immunohisotchemical analysis of paraffin-embedded human tonsil using TRAF1 (1F3) Rat mAb. 免疫组织化学分析石蜡包埋的人扁桃体切片，使用抗体为 TRAF1 (1F3) Rat mAb 兔单抗。 |
