| 货号 | 3576S |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | W/IHC-P/IF-IC/F |
| 目标/特异性 | CD56 (NCAM) (123C3) Mouse mAb detects endogenous levels of total CD56 protein. |
| 使用方法 | WB(1:1000) IHC-P (1:800) F (1:400) IF-IC (1:400) |
| 供应商 | CST |
| 背景 | NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains (1). NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma (2). CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 also express CD56 (3). |
| 存放说明 | -20C |
| 计算分子量 | 120 to 220 |
Immunohistochemical analysis of paraffin-embedded human neuroblastoma, using CD56 (NCAM) (123C3) Mouse mAb.使用CD56 (NCAM) (123C3) 小鼠单抗对石蜡包埋的人成神经细胞瘤组织进行免疫组化分析。 | |
Confocal immunofluorescent analysis of SH-SY5Y cells (left) and HeLa cells (right) using CD56 (NCAM) (123C3) Mouse mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).使用CD56 (NCAM) (123C3)小鼠单抗（绿色）对SH-SY5Y cells (左)和 HeLa (右)进行激光共聚焦免疫荧光分析。蓝色假色=DRAQ5® #4084(DNA荧光染料)。 |
