| 货号 | 76437T |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit IgG |
| 应用 | IHC-P, F , IF-IC |
| 目标/特异性 | CD68 (D4B9C) XP® Rabbit mAb recognizes endogenous levels of total CD68 protein. |
| 使用方法 | IHC-P IF-IC F |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | CD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1, 2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3, 4). |
| 存放说明 | -20C |
| 参考文献 | 1 . Rabinowitz, S.S. and Gordon, S. (1991) J Exp Med 174, 827-36. 2 . Holness, C.L. and Simmons, D.L. (1993) Blood 81, 1607-13. 3 . Ramprasad, M.P. et al. (1995) Proc Natl Acad Sci U S A 92, 9580-4. 4 . Ramprasad, M.P. et al. (1996) Proc Natl Acad Sci U S A 93, 14833-8. |
Confocal immunofluorescent analysis of THP-1 (left) and Jurkat (right) cells using CD68 (D4B9C) XP® Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). Projected images from a z-stack series are shown. | |
Immunohistochemical analysis of paraffin-embedded human tonsil using CD68 (D4B9C) XP® Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded THP-1 (left) and Jurkat (right) cell pellets using CD68 (D4B9C) XP® Rabbit mAb. | |
Flow cytometric analysis of human peripheral blood mononuclear cells co-stained with anti-human CD14 using CD68 (D4B9C) XP® Rabbit mAb (right) compared to a concentration-matched Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (left). Anti-rabbit IgG (H+L), F(ab)2 Fragment (Alexa Fluor® 488 Conjugate) #4412 was used as a secondary antibody. | |
Flow cytometric analysis of Jurkat cells (blue) and THP-1 cells (green) using CD68 (D4B9C) XP® Rabbit mAb. Anti-rabbit IgG (H+L), F(ab)2 Fragment (Alexa Fluor® 488 Conjugate) #4412 was used as a secondary antibody. | |
Immunohistochemical analysis of paraffin-embedded human serous papillary carcinoma of the ovary using CD68 (D4B9C) XP® Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using CD68 (D4B9C) XP® Rabbit mAb. |
