| 货号 | 13176T |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human,Mouse,Rat, |
| 来源宿主 | Rabbit IgG |
| 应用 | WB, IP , IHC-P , IF-F |
| 目标/特异性 | Calbindin (D1I4Q) XP® Rabbit mAb recognizes endogenous levels of total calbindin protein. |
| 使用方法 | WB(1:1000) IP (1:50) IHC-P (1:800) IF-F (1:200) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Calcium-binding proteins of different subfamilies regulate the second messenger calcium. Calbindin, calmodulin, S-100, parvalbumin and troponin C are members of the low molecular weight calcium-binding protein family (1). Calbindin is expressed in discrete neuronal populations within the CNS and is thought to act as an intracellular calcium buffering protein. Most Purkinje cells express calbindin, which is expressed when neurons start to migrate and differentiate. In contrast, other calcium buffering proteins, such as parvalbumin, are expressed later during development and in parallel with increasing neuronal activity (2). |
| 存放说明 | -20C |
| 计算分子量 | 28 |
| 参考文献 | 1 . Kawasaki, H. et al. (1998) Biometals 11, 277-95. 2 . Bastianelli, E. (2003) Cerebellum 2, 242-62. |
Confocal immunofluorescent analysis of normal rat brain using Calbindin (D1I4Q) XP®Rabbit mAb (green) and GFAP (GA5) Mouse mAb #3670 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). | |
共聚焦免疫荧光分析正常大鼠脑组织，使用的抗体是Calbindin (D1I4Q) XP® Rabbit mAb 兔单抗(绿色) 和GFAP (GA5) Mouse mAb 鼠单抗 #3670 (红色)。蓝色伪彩= DRAQ5® #4084 (荧光 DNA 染料)。 | |
