Perilipin (D1D8) XP® Rabbit mAb【科瑞奥博】

产品中心

当前位置：首页>产品中心

Perilipin (D1D8) XP® Rabbit mAb

货号： 9349T 基本售价： 1550.0 元规格： -

产品信息

概述
货号	9349T
同种亚型	Rabbit IgG
反应种属	Human,Mouse,
来源宿主	Rabbit IgG
应用	WB, IP , IHC-P , IF-F , IF-IC
目标/特异性	Perilipin (D1D8) XP® Rabbit mAb detects endogenous levels of total perilipin protein.
使用方法	WB(1:1000) IP (1:50) IHC-P (1:100) IF-F (1:200) IF-IC (1:200)

性能
供应商	CST
灵敏度	Endogenous
背景	Triacylglycerol is stored in lipid droplets as a primary energy reserve. Perilipin is localized at the periphery of lipid droplets and serves as a protective coating against lipases (1-3). Evidence suggests that PKA regulates lipolysis by phosphorylating perilipin (1,2,4,5). Phosphorylation of perilipin results in the conformational change that exposes lipid droplets to endogenous lipases, such as hormone-sensitive lipases (2). Hence, perilipin plays a pivotal role in lipid storage (2,5).
存放说明	-20C
计算分子量	62
参考文献	1 . Greenberg, A.S. et al. (1991) J Biol Chem 266, 11341-6. 2 . Brasaemle, D.L. (2007) J Lipid Res 48, 2547-59. 3 . Ducharme, N.A. and Bickel, P.E. (2008) Endocrinology 149, 942-9. 4 . Egan, J.J. et al. (1990) J Biol Chem 265, 18769-75. 5 . Brasaemle, D.L. et al. (2009) Mol Cell Biochem 326, 15-21.

参考图片

Immunohistochemical analysis of parafin-embedded mouse brown fat using Perilipin (D1D8) XP® Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right).

免疫组化检测小鼠棕色脂肪石蜡切片，左图为对照肽段，右图为抗原特异性肽段。所用抗体为Perilipin (D1D8) XP® Rabbit mAb兔单抗。

Immunohistochemical analysis of paraffin-embedded breast carcinoma using Perilipin (D1D8) XP® Rabbit mAb. Note specific staining of adipocytes.

免疫组化检测乳腺癌组织石蜡切片，所用抗体为Perilipin (D1D8) XP® Rabbit mAb兔单抗。注意图中脂肪细胞的特异性染色。

Western blot analysis of extracts from human pre-adipocytes and adipocytes using Perilipin (D1D8) XP® Rabbit mAb (upper) and β-Actin Antibody #4967 (lower).

Western blot检测人前脂肪细胞和脂肪细胞提取物，所用抗体为Perilipin (D1D8) XP® Rabbit mAb (上)和β-Actin Antibody #4967(下)。

Confocal immunofluorescent analysis of 8-day differentiated 3T3-L1 cells, using Perilipin (D1D8) Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

免疫荧光共聚焦显微镜观察分化8天的3T3-L1细胞，所用抗体为Perilipin (D1D8) Rabbit mAb兔单抗(绿色)。蓝色伪彩为 DRAQ5® #4084(DNA荧光染料)。

Confocal immunofluorescent analysis of frozen mouse brown adipose tissue using Perilipin (D1D8) XP® Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

免疫荧光共聚焦显微镜观察小鼠棕色脂肪冰冻组织，所用抗体为Perilipin (D1D8) XP® Rabbit mAb兔单抗 (绿色)。蓝色伪彩为DRAQ5® #4084 (DNA荧光染料)。