| 货号 | 2598T |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human,Mouse,Rat,Monkey, |
| 来源宿主 | Rabbit IgG |
| 应用 | WB, IP , IF-IC |
| 目标/特异性 | NUP98 (C39A3) Rabbit mAb detects endogenous levels of total NUP98 protein. |
| 使用方法 | WB(1:1000) IP (1:50) IF-IC (1:50) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | NUP98 (nucleoporin 98 kDa) is a component of the nuclear pore complex. It is expressed as three different precursors that undergo auto-cleavage to generate a common amino-terminal 98 kDa peptide (NUP98) and carboxy-terminal 6, 96 (NUP96) and 88 (p88) kDa peptides (1-2). NUP98 contains FG and GLFG repeat domains at its amino terminus and a RNA-binding domain in its carboxy terminus (3). The NUP98 gene is localized on chromosome 11p15.5, a region frequently rearranged in leukemias. To date, 15 fusion partners have been identified for NUP98 (4-5). |
| 存放说明 | -20C |
| 计算分子量 | 98 |
| 参考文献 | 1 . Fontoura, B.M. et al. (1999) J Cell Biol 144, 1097-112. 2 . Rosenblum, J.S. and Blobel, G. (1999) Proc Natl Acad Sci U S A 96, 11370-5. 3 . Griffis, E.R. et al. (2004) Mol Biol Cell 15, 1991-2002. 4 . Slape, C. and Aplan, P.D. (2004) Leuk Lymphoma 45, 1341-50. 5 . Nakamura, T. (2005) Int J Hematol 82, 21-7. |
Western blot analysis of cell extracts from various cell types using NUP98 (C39A3) Rabbit mAb. 使用NUP98 (C39A3) Rabbit mAb，免疫印迹（Western Blot）分析不同细胞中NUP98 (C39A3)蛋白水平。 | |
Confocal immunofluorescent analysis of Caki-1 cells using NUP98 (C39A3) Rabbit mAb (green). Actin filaments have been labeled with Alexa Fluor® 555 phalloidin (red). 使用NUP98 (C39A3) Rabbit mAb兔单抗 (绿色)标记，共聚焦免疫荧光分析Caki-1细胞。Alexa Fluor® 555 phalloidin标记微丝蛋白(red)。 |
