| 货号 | 3497T |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human,Mouse,Rat,Monkey, |
| 来源宿主 | Rabbit IgG |
| 应用 | WB, IP |
| 目标/特异性 | PHF2 (D45A2) Rabbit mAb detects endogenous levels of total PHF2 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Plant homeodomain (PHD) finger protein 2 (PHF2) is a putative transcription factor. PHF2 contains a zinc finger-like PHD domain that is distinct from other classes of zinc finger motifs and is often found in proteins that influence chromatin structure (1). It also contains a Jumonji C (JmjC) domain, which may play a role in histone demethylation (2). The PHF2 gene is ubiquitously expressed in adult mouse tissues; however, the majority of PHF2 expression in the mouse embryo occurs in the neural tube and root ganglia (1). PHF2 mutations have been associated with both early- and late-onset breast carcinoma (3). |
| 存放说明 | -20C |
| 计算分子量 | 150 |
| 参考文献 | 1 . Hasenpusch-Theil, K. et al. (1999) Mamm Genome 10, 294-8. 2 . Klose, R.J. et al. (2006) Nat Rev Genet 7, 715-27. 3 . Sinha, S. et al. (2008) Mol Cancer 7, 84. |
Western blot analysis of extracts from various cell lines using PHF2 (D45A2) Rabbit mAb. 使用PHF2 (D45A2) Rabbit mAb，免疫印迹(Western blot)分析不同细胞中PHF2 (D45A2)的蛋白水平。 |
