货号 | 8164T |
同种亚型 | Rabbit IgG |
反应种属 | Human,Monkey, |
来源宿主 | Rabbit IgG |
应用 | WB, IP |
目标/特异性 | PFKP (D4B2) Rabbit mAb recognizes endogenous levels of total PFKP protein. |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
灵敏度 | Endogenous |
背景 | Phosphofructokinase (PFK) catalyzes the phosphorylation of fructose-6-phosphate in glycolysis (1). There are three isozymes: muscle-type, liver-type, and platelet-type (2,3). Platelet-type phosphofructokinase (PFKP) is expressed in various cell types (4,5). Research studies have shown that genetic variations in PFKP are associated with individuals born small for gestational age that are prone to obesity and diabetes later in adulthood (6). |
存放说明 | -20C |
计算分子量 | 80 |
参考文献 | 1 . Mediavilla, D. et al. (2008) J Biochem 144, 235-44. 2 . Eto, K. et al. (1994) Biochem Biophys Res Commun 198, 990-8. 3 . Hannemann, A. et al. (2005) Gene 345, 237-47. 4 . Morrison, N. et al. (1992) Hum Genet 89, 105-6. 5 . Vora, S. (1983) Isozymes Curr Top Biol Med Res 11, 3-23. 6 . Morgan, A.R. et al. (2010) BMC Med Genet 11, 125. |
Western blot analysis of extracts from various cell lines using PFKP (D4B2) Rabbit mAb. Wetern blot方法检测多种细胞系提取物,所用抗体为PFKP (D4B2) Rabbit mAb兔单抗。 |