PepTivator HPV18 E6, human, 60 nmol
货号:
130-096-006 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-096-006 |
描述 | PepTivator® HPV18 E6 is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the complete sequence of the human papillomavirus (HPV)18 E6 protein (UniProt ID: P06463).PepTivator peptide pools have been developed for the efficient in vitro stimulation of antigen–specific T cells, as peptides of 15 amino acids in length and 11 amino acids overlap represent an optimized solution for stimulating both CD4+ and CD8+ T cells in various applications.Quantitative, phenotypical, or functional analysis of HPV18 E6–specific T cell immunity can provide important information on the natural course of immune responses in healthy or immunocompromised individuals. |
性能供应商 | Miltenyi |
背景 | HPVs are non-enveloped, double-stranded circular DNA viruses. Persistent infections with several HPV types are associated with the development of tumors. HPV types 16 and 18 together cause about 70 percent of cervical cancers. The viral E6 and E7 proteins of HPV16 and HPV18 are involved in the initiation and maintenance of oncogenic processes. HPV E6– and E7–specific T cell immune responses play an important role in successfully clearing HPV infection and controlling HPV-associated diseases. |