PepTivator CMV IE-1, human, 60nmol
货号:
130-093-494 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-093-494 |
描述 | The PepTivator® CMV IE-1 is a peptide pool that consists mainly of 15-mer peptides with 11–amino acid overlap, covering the complete sequence of the cytomegalovirus IE-1 protein (UniProt ID: P13202).PepTivator peptide pools have been especially developed for the efficient in vitro stimulation of antigen–specific CD4+ and CD8+ T cells, as peptides of 15 aa length with 11-aa overlap represent an optimized solution for stimulating both CD4+ and CD8+ T cells in various applications.1Quantitative, phenotypical, or functional analysis of CMV IE-1–specific T cell immunity can provide important information on the natural course of immune responses in healthy or immunocompromised individuals. |
性能供应商 | Miltenyi |
背景 | CMV IE-1 (immediate early protein 1), also known as UL123, is a non-structural protein, one of the first CMV antigens expressed in an infected cell, and predominantly induces a CD8+ T cell response. IE-1-specific T cells occur in infected individuals at frequencies comparable to those of pp65-specific CD8+ T cells.2Both CMV antigens, IE-1 and pp65, are considered dominant T cell targets. |