PepTivator Survivin 1, human, 60 nmol
货号：
130-094-443 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-094-443 |
| 描述 | PepTivator® Survivin 1 is a peptide pool that consists mainly of 15-mer peptides with 11-amino acid (aa) overlap, covering the complete sequence of the human survivin protein (UniProt ID: O15392).PepTivator peptide pools have been developed for the efficient in vitro stimulation of antigen–specific CD4+ and CD8+ T cells as peptides of 15-aa length with 11-aa overlap represent an optimized solution for stimulating both CD4+and CD8+ T cells in various applications.1Quantitative, phenotypical, or functional analysis of Survivin 1–specific T cell immunity can provide important information on the natural course of immune responses. |
性能| 供应商 | Miltenyi |
| 背景 | Survivin is a bifunctional protein that suppresses apoptosis and regulates mitosis. It is expressed during development in proliferating cells, but remains absent in differentiated tissue. In most human solid malignancies and in leukemia elevated levels of survivin are found contributing to the survival and proliferation of tumor cells. In cancer patients survivin-specific T cell reactivity has been observed. Thus, survivin is described as a candidate target antigen for immunotherapeutic interventions.2 |
