PepTivator MAGE-A3, human, 6 nmol
货号：
130-095-384 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-095-384 |
| 描述 | PepTivator® MAGE-A3 is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the complete sequence of the human MAGE-A3 protein (UniProt ID: P43357).PepTivator peptide pools have been developed for the efficient in vitro stimulation of antigen–specific T cells, as peptides of 15 amino acids in length and 11 amino acids overlap represent an optimized solution for stimulating both CD4+ and CD8+ T cells in various applications.Quantitative, phenotypical, or functional analysis of MAGE-A3–specific T cell immunity can provide important information on the natural course of immune responses. |
性能| 供应商 | Miltenyi |
| 背景 | Melanoma-associated antigen 3 (MAGE-A3) belongs to the cancer testis family antigens. Expression is limited to male germ cells in normal tissue. It is aberrantly expressed in tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma, breast carcinoma, and hematological malignancies. MAGE-A3 was described to be an attractive antigen to monitor antitumor T cell responses and to be used for immunotherapeutic interventions.1,2 |
