Slan (M-DC8+) Monocyte Isolation Kit
货号：
130-093-026 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-093-026 |
| 描述 | The Slan (M-DC8) Monocyte Isolation Kit was designed for the magnetic separation of human Slan (M-DC8)+ cells. The kit contains CD3 MicroBeads for efficient depletion of contaminating T cells, FcR Blocking Reagent and Anti-Slan (M-DC8) MicroBeads. |
性能| 供应商 | Miltenyi |
| 背景 | Slan (6-Sulfo LacNAc) is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1), characteristically expressed on a new subset of PBMCs with features closely related to CD16+CD14lowmonocytes. Freshly isolated Slan (MDC-8)+ cells produce TNF-α following stimulation with LPS. Moreover, they are involved in antibody-dependant cell-mediated cytotoxicity and promote proliferation, IFN-γ production and tumor directed cytotoxicity of NK cells. Upon stimulation with IFN-γ, Slan (M-DC8)+ cells exhibit the ability to directly lyse tumor cell lines in vitro. Additionally, Slan (M-DC8)+ cells are potent producers of early IL-12 upon stimulation. |
