货号 | 3329S |
反应种属 | Human |
来源宿主 | Rat IgG1 |
应用 | W/IF-IC/F |
目标/特异性 | MNDA (3C1) Rat mAb detects endogenous levels of total MNDA protein. |
使用方法 | WB(1:1000) F (1:200) IF-IC (1:800) |
供应商 | CST |
背景 | MNDA (myeloid cell nuclear differentiation antigen) is a transcription factor constitutively expressed in peripheral blood granulocytes and monocytes; low expression is also found in a subset of B cells (1,2). MNDA is a member of the interferon (IFN)-regulated 200 family of genes, which contain one or more copies of a partially conserved domain of 200 amino acid residues thought to mediate protein-protein interaction (3). MNDA may play a role in apoptosis and its expression is reduced in myelodysplastic syndromes (MDS) (4). MNDA has been proposed to be a marker for nodal marginal zone lymphoma (5). |
存放说明 | -20C |
计算分子量 | 50 |
Western blot analysis of extracts from HL-60 and THP-1 cells using MNDA (3C1) Rat mAb.Western免疫印迹。用 MNDA (3C1) Rat mAb研究HL-60和THP-1细胞的细胞提取液。 | |
Flow cytometric analysis of Jurkat cells (red) and THP-1 cells (blue) using MNDA (3C1) Rat mAb.流式细胞仪分析Jurkat细胞(红色)和THP-1细胞(蓝色),所用抗体为MNDA (3C1) Rat mAb。 | |
Confocal immunofluorescent analysis of THP-1 cells (left) and Jurkat cells (right) using MNDA (3C1) Rat mAb (green). Actin filaments were labeled with DY-554 phalloidin (red).共聚焦免疫荧光分析THP-1细胞 (左图) 和 Jurkat 细胞(右图),所用抗体为MNDA (3C1) Rat mAb (绿色)。肌动蛋白微丝用 DY-554 phalloidin (红色)标记。 |