Human p53 Allophycocyanin MAb (Clone 184727) (100 TESTS)【科瑞奥博】

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Human p53 Allophycocyanin MAb (Clone 184727) (100 TESTS)

货号： IC13551A 基本售价： 5086.1 元规格： 100 Tests

产品信息

概述
货号	IC13551A
别名	Antigen NY-CO-13; BCC7; FLJ92943; LFS1; LFS1TRP53; p53 tumor suppressor; p53; P53cellular tumor antigen p53; Phosphoprotein p53; TP53; transformation-related protein 53; TRP53; tumor protein p53; Tumor suppressor p53
反应种属	Human
应用	Intracellular Staining by Flow Cytometry
目标/特异性	Detects human p53.
使用方法	Intracellular Staining by Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	7157 (Human); 22059 (Mouse); 24842 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human p53 Asp7-Asp393 Accession # P04637
生物活性	Human
标记	Allophycocyanin
背景	The p53 tumor suppressor protein is a multi-functional transcription factor that regulates cellular decisions regarding proliferation, cell cycle checkpoints, and apoptosis. The importance of p53 is underscored by its mutation in over 50% of human cancers. Mice that lack one or both copies of p53 also showed an increased incidence of tumors, which makes the p53 deficient mouse a model system for studying cancer generation and progression.
运输条件	Blue Ice
存放说明	4℃
参考文献	Apoptosis Transcription Factors and Regulators Cancer Biomarkers Cancer Stem Cell Transcription Factors Cell Cycle Checkpoint DNA Damage and Repair Epithelial Stem Cell Transcription Factors Hematopoietic Stem Cell Transcription Factors and Regulators ICC / IHC Images: p53 Immunoglobulin-Like Domain Transcription Factors Mesenchymal Stem Cell Transcription Factors Mini-review: DNA Damage Response Mini-review: Genomic Instability Syndromes Neural Stem Cell Transcription Factors p53 Pathway p53: More than a Transcription Factor? Parkinsons Disease Related Molecules Pluripotent Stem Cell Transcription Factors TNF Superfamily Regulators Transcription Factors and Regulators Transcription Factors in the Akt Pathway

参考图片

Detection of p53 in MCF‑7 Human Cell Line by Flow Cytometry. MCF‑7 human breast cancer cell line treated (filled histogram) with camptothecin (CPT) or untreated (open histogram) was stained with Mouse Anti-Human p53 APC‑conjugated Monoclonal Antibody (Catalog # IC13551A). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.