Human FGF R2 Allophycocyanin MAb (Clone 98725) (100 TESTS)
货号：
FAB684A 基本售价：
4808.5 元 规格：
100 Tests
产品信息
概述| 货号 | FAB684A |
| 别名 | BFR-1; CD332 antigen; CD332; CFD1; craniofacial dysostosis 1; EC 2.7.10; EC 2.7.10.1; fibroblast growth factor receptor 2; FLJ98662; Jackson-Weiss syndrome; JWS; Keratinocyte growth factor receptorreceptor like 14; KSAM; K-sam; soluble FGFR4 variant 4 |
全称 | Fibroblast Growth Factor Receptor 2 | | 反应种属 | Human |
| 应用 | Flow Cytometry(10 µL/106cells)
|
| 目标/特异性 | Detects alpha isoforms (3 Ig-like domains) and beta isoforms (2 Ig-like domains) of human FGF R2 in direct ELISAs and Western blots. In direct ELISAs, this antibody reacts with all isoforms of rhFGF R2 but shows approximately a 4-fold preference for (IIIc) isoforms. Approximately 100% cross-reactivity with recombinant mouse FGF R2, 15% cross-reactivity with recombinant human (rh) FGF RI ( beta isoforms), and no cross-reactivity with rhFGF RI ( alpha isoforms), rhFGF R3, or rhFGF R4 is observed. |
| 使用方法 | Flow Cytometry: 10 µL/106cells
|
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2263 (Human); 14183 (Mouse) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human FGF R2 isoforms and Mouse myeloma cell line NS0-derived recombinant human FGF R2 isoforms |
| 生物活性 | Human |
| 标记 | Allophycocyanin |
| 背景 | FGF R2 is a transmembrane tyrosine kinase that functions as a receptor for several FGF family proteins. The extracellular domain includes three ( alpha isoforms) or two ( beta isoforms) Ig-like domains. Alternative exon usage results in IIIb or IIIc isoforms that differ in their membrane proximal Ig-like domain. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - FGF Family
- FGF Ligands
- FGF Regulators
- Fibroblast Growth Factor Superfamily
- Fibroblast Growth Factors and their Receptors
- Glial Lineage Markers
- Human CD Marker Products
- ICC / IHC Images: FGF R2
- Mesenchymal to Epithelial Transition
- Mini-review: Fibroblast Growth Factors (FGFs)
- Neural Stem Cell Markers
- Receptor Tyrosine Kinases (RTKs)
- Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
- Receptors in the Jak/STAT Pathway
|
参考图片Detection of FGF R2 in KATO-III Human Cell Line by Flow Cytometry. KATO-III human gastric carcinoma cell line was stained with Mouse Anti-Human FGF R2 APC-conjugated Monoclonal Antibody (Catalog # FAB684A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins. |
