| 货号 | IC5875V-100UG |
| 别名 | TLR7; toll-like receptor 7 | 全称 | Toll-like Receptor 7 |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human TLR7 in direct ELISAs. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 51284 (Human); 170743 (Mouse); 317468 (Rat) |
| 免疫原 | E. coli-derived recombinant human TLR7 Met360-Leu516 Accession # Q9NYK1 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 405 |
| 背景 | Toll-like receptor 7 (TLR7) is a 120 kDa (predicted, unglycosylated) type I transmembrane glycoprotein and member of the Toll-like receptor family. Human TLR7 is synthesized as a 1049 amino acid (aa) precursor that contains a 26 aa signal sequence, an 803 aa extracellular domain (ECD), a 21 aa transmembrane sequence, and a 189 aa cytoplasmic domain. Mature human TLR7 is 81% aa identical to mature mouse TLR7. TLR7 is detected in brain, placenta, spleen, stomach, small intestine, lung, and in plasmacytoid pre-dendritic cells. Functionally, TLR7 participates in the innate immune response to microbial agents. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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