| 货号 | FAB4665U-100UG |
| 别名 | inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; NAALADase L2; NAALADase like 2; NAALADase-like 2; NAALADL2; N-acetylated alpha-linked acidic dipeptidase 2; N-acetylated alpha-linked acidic dipeptidase-like 2 | 全称 | N-Acetylated Alpha-Linked Acidic Dipeptidase-like 2 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human NAALADase‑like 2/NAALADL2 in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 254827 (Human); 635702 (Mouse); 499583 (Rat) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human NAALADase‑like 2/NAALADL2 Ser152-Asn795 Accession # Q58DX5 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 350 |
| 背景 | NAALADL2 (N-acetylated alpha -linked acidic dipeptidase like 2) is a member of the peptidase M28 family of enzymes. It is presumably a type II transmembrane (TM) protein that may have O-glycosyl hydrolase activity. Human NAALADL2 is 795 amino acids (aa) in length. It is believed to contain a cytoplasmic and TM segment at the N-terminus, followed by a peptidase domain (aa 444‑596) and a TfR-like dimerization region (aa 688‑777). There are multiple splice forms. One shows a 4 aa substitution for aa 292‑795, a second shows an alternate start site at Met18 with a 24 aa substitution for aa 314‑795, and a third contains an alternate start site at Met283, accompanied by a deletion of aa 363‑411 and 633‑795. Over aa 152‑795, human NAALADL2 shares 87% and 82% aa sequence identity with mouse and canine NAALADL2, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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