CD178-APC, human
货号：
130-096-458 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-096-458 |
| 描述 | Clone NOK-1 reacts with CD178, a type II transmembrane glycoprotein, also known as Fas ligand or CD95L. It is expressed on activated lymphocytes, e.g., T cells, NK cells, monocytes, or granulocytes, as well as at immune-privileged sites, e.g., cornea or testis. CD178 can trigger apoptosis through trimerization of the Fas receptor CD95. Thereby, CD178 and CD95 play a key role in the regulation of the immune system. Cleavage of membrane-bound CD178 from the cell surface via matrix metalloproteinases (such as MMP-7) generates soluble CD178 molecules. |
| 别名 | FASLG, ALPS1B, APT1LG1, APTL, CD95L, FasL, TNFSF6 |
| 克隆号 | NOK-1 |
| 同种亚型 | mouse IgG1κ |
