CD16-Biotin, human
货号:
130-098-386 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-098-386 |
描述 | CD16 is a 50–80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form is found on human NK cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form is present on neutrophils.The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone VEP13 recognizes both the extracellular domain of the transmembrane form as well as the GPI-linked form of the human CD16 antigen. CD16 is expressed on the majority of rhesus monkey NK cells and on a subset of monocytes but not on granulocytes. |
别名 | FcγRIIIA, FcγRIIIB, FcR-10, IGFR3, IMD20 |
克隆号 | VEP13 |
同种亚型 | mouse IgMκ |