CD32 pure, human
货号：
130-108-021 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-108-021 |
| 描述 | FcγRII (CD32) is a 40 kDa low affinity receptor for the Fc fragment of aggregated IgG. Due to alternative splicing three different isoforms of CD32 are expressed on hematopoietic cells: FcRIIA, FcRIIB, and FcRIIC. The cytoplasmic domains of FcRIIA and FcRIIC contain an activatory ITAM motif whereas FcRIIB is an inhibitory receptor containing an ITIM motif. Different isoforms of CD32 are expressed on B cells, monocytes, dendritic cells, granulocytes, and platelets. The monoclonal antibody 2E1 recognizes all isoforms of CD32 without blocking the binding of immune complexes. |
| 别名 | FCGR2A, CD32A, CDw32, FCG2, FCGR21, FcGR, IGFR2, FCGR2B, CD32B, FcγRII |
| 克隆号 | 2E1 |
| 同种亚型 | mouse IgG2a |
