CD85g (ILT7)-PE-Vio770, human 30 tests
货号：
130-099-010 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-099-010 |
| 描述 | The clone REA100 recognizes human CD85g, also known as immunoglobulin-like transcript 7 (ILT7), a cell surface receptor which is specifically expressed on human plasmacytoid dendritic cells (PDCs). ILT7 associates with FcεR1γ chain through positively charged arginine residue located in the transmembrane domain to form a receptor complex. Cross-linking of ILT7 results in FcεR1γ-dependent activation of an ITAM-mediated signaling pathway, which negatively influences TLR7/9 induced type I IFN production. Cross-linking of ILT7 by REA100 monoclonal antibodies inhibits type I IFN production in human PDCs.Additional information: Clone REA100 display negligible binding to Fc receptors. |
| 别名 | LILRA4, ILT7 |
| 克隆号 | REA100 |
| 同种亚型 | recombinant human IgG1 |
