CD54 (ICAM-1)-PE-Vio770, human 30 tests
货号：
130-104-063 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-104-063 |
| 描述 | Clone REA266 recognizes human CD54, a 85–110 kDa type I transmembrane glycoprotein, which also known as intercellular adhesion molecule 1 (ICAM-1). CD54 is continuously present in low concentrations in the membranes of monocytes/macrophages, lymphocytes, activated endothelial cells, granulocytes, and dendritic cells. Its expression is regulated by inflammatory cytokines and can be induced by interleukin-1 and tumor necrosis factor. CD54 is a ligand for LFA-1, a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via CD54/LFA-1 and then transmigrate into tissues. CD54 has been shown to interact with CD11a, EZR, and CD18. More recently, CD54 has been characterized as a site for the cellular entry of human rhinovirus.Additional information: Clone REA266 displays negligible binding to Fc receptors. |
| 别名 | ICAM-1, BB2, P3.58 |
| 克隆号 | REA266 |
| 同种亚型 | recombinant human IgG1 |
