Anti-CX3CR1-PE-Vio770, human 30 tests
货号：
130-100-405 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-405 |
| 描述 | CX3CR1 is a transmembrane chemokine receptor with a molecular mass of 40 kDa. It binds the chemokine CX3CL1, also known as fractalkine or neurotactin. Binding of CX3CR1 to the membrane‑bound form of fractalkine promotes cell-cell adhesion, wheras the soluble form induces cell migration of CX3CR1-bearing cells such as monocytes, NK cells, T cells, dendritic cells (DCs), and macrophages including microglia.¹ CX3CR1 plays also an important role in the formation of transepithelial dendrites by intestinal DCs.² Failure in the fractalkine/CX3CR1 interaction may contribute to the development of several inflammatory diseases including atherosclerosis, psoriasis, rheumatoid arthritis, and experimental autoimmune myositis. |
| 别名 | CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28 |
| 克隆号 | 2A9-1 |
| 同种亚型 | rat IgG2bκ |
