CD202b pY1102-APC, human 30 tests
货号：
130-109-478 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-109-478 |
| 描述 | Clone REA583 recognizes the Y1102-phosphorylated form of CD202b, which is 145 kDa type I transmembrane tyrosine kinase receptor. CD202b is composed of an amino-terminal ligand binding domain with immunoglobulin domains, epithelial growth factor repeats, and fibronectin-like 3 repeats, a single transmembrane domain, and an intracellular tyrosine kinase domain. Expression of CD202b is found on endothelial cells and a subpopulation of monocytes. Angiopoietins are the natural ligands of CD202b. Activation of CD202b dependent signaling pathways are involved in survival and apoptosis of endothelial cells, in controlling vascular permeability, and regulation of the capillary sprouting that occurs during normal angiogenesis. Additional information: Clone REA583 displays negligible binding to Fc receptors. |
| 别名 | TIE2, TIE-2, p140 TEK |
| 克隆号 | REA583 |
| 同种亚型 | recombinant human IgG1 |
