Anti-ROR-1-VioBright FITC, h 30 tests
货号：
130-104-647 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-104-647 |
| 描述 | The monoclonal antibody 2A2 reacts with human receptor tyrosine kinase-like orphan receptor (ROR)1. ROR1 has characteristics of an oncofetal gene and was recently identified to be overexpressed at the gene and protein levels in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). ROR1 expression has also been detected in ovarian cancer, renal cancer, melanoma, and lung adenocarcinoma, suggesting a general role of ROR1 in cancer genesis and/or maintenance. Moreover, ROR1 expression has been found in undifferentiated embryonic stem cells, in adipose tissue, at early stages of B cell development, but not in major adult tissues. Therefore, ROR1 is a potential therapeutic target and a biomarker to identify and enumerate malignant cells in CLL and MCL blood samples via flow cytometry. |
| 别名 | NTRKR1 |
| 克隆号 | 2A2 |
| 同种亚型 | mouse IgG1κ |
