Anti-AKT1-PerCP-Vio700, human 30 tests
货号：
130-100-744 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-744 |
| 描述 | Clone REA134 recognizes AKT1, which is also known as protein kinase Bα. AKT1 is a serine/threonine protein kinase, belonging to the AKT family of kinases and like each AKT family member, contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a carboxyl-terminal regulatory domain with a hydrophobic motif (HM). Activation of AKT1 is achieved via phosphorylation at multiple sites, which take place in response to engagement of receptors such as platelet derived growth factor receptor (PDGF-R). Activated AKT1 further phosphorylates and alters the activity of several downstream substrates allowing AKT1 to play a vital role in various biological processes such as cell growth, survival, migration, and proliferation. Additional information: Clone REA134 displays negligible binding to Fc receptors. |
| 别名 | AKT, CWS6, PKB, PRKBA, RAC, RAC-ALPHA, PKBα |
| 克隆号 | REA134 |
| 同种亚型 | recombinant human IgG1 |
