CD39-VioBlue, human 30 tests
货号:
130-106-595 基本售价:
询价 规格:
30 tests
产品信息
概述货号 | 130-106-595 |
描述 | The CD39 antibody specifically recognizes the membrane-bound human CD39 antigen, which is expressed on an effector/memory-like subset of FoxP3+ regulatory T cells. CD39 is an ectonucleotidase and catalyzes the hydrolysis of extracellular nucleotides, for example, ATP. In concert with CD73, which is an ecto-5’-nucleotidase, this can lead to the production of adenosine. High extracellular ATP concentrations indicate tissue injury and cell death and induce various pro-inflammatory responses in immune cells.Through its enzymatic activity, CD39 can contribute to the suppressive function of regulatory T cells, for example, by eliminating extracellular ATP or by generating adenosine, which has suppressive effects on various immune cells. |
别名 | Entpd1, ATPDase, NTPDase-1, SPG64, EC3.6.1.5, gp80 |
克隆号 | MZ18-23C8 |
同种亚型 | mouse IgG1κ |