CD7-VioBlue, human 30 tests
货号：
130-106-508 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-106-508 |
| 描述 | Clone CD7-6B7 recognizes the human CD7 antigen, a single-pass type I membrane protein, also known as leu-9 or GP40. CD7 appears early in T cell ontogeny and is expressed by most T cells in the periphery. It is also found on NK cells, hematopoietic progenitors, monocytes, acute lymphocytic leukemia, and some acute myeloid leukemia cells. Although the ligand is yet not identified, CD7 has been recognized as a costimulatory molecule. CD7 activates phosphatidylinositol 3-kinase which is involved in CD7-mediated regulation of integrin adhesiveness. Furthermore, it has been reported that the β-galactoside-binding lectin galectin-1 binds CD7, leading to induction of apoptosis of thymocytes and T cells, with implications for certain autoimmune diseases and T cell lymphomas. |
| 别名 | GP40, Leu-9, TP41, Tp40 |
| 克隆号 | CD7-6B7 |
| 同种亚型 | mouse IgG2aκ |
